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Process synthesis with simultaneous consideration of inherent safety-inherent risk footprint

Andreja Nemet, Jiří J. Klemeš, Zdravko Kravanja

《化学科学与工程前沿（英文）》 2018年第12卷第4期页码 745-762 doi: 10.1007/s11705-018-1779-7

摘要：

Process plants should be designed to be economically viable and environmentally friendly, while also being operable and maintainable during process implementation. The safety of processes is among the most important considerations in obtaining results that are more acceptably realistic, as it is linked to the availability and reliability of the process. Inherent safety can effectively be enhanced in the early stages of the design, when the main decisions on process design are made. The aim of this study is to enhance and select the appropriate risk assessment method and to incorporate it into process synthesis, using a mathematical programming approach. A mixed-integer, nonlinear programming (MINLP) model was used for the synthesis of a methanol production process, considering risk assessment during the synthesis. Risk assessment is performed simultaneously with the MINLP process synthesis, where the risk is determined either for the whole process as overall risk, or on a per unit-of-a-product basis. For the latter, a new measurement is proposed: the inherent risk footprint. The results of a case study led to two main conclusions: (i) Significantly safer designs can be obtained at negligible economic expense, and (ii) at higher production capacities, a lower inherent risk footprint can be achieved. The results also indicate that designs obtained using this method can have significantly increased inherent safety, while remaining economically viable.

关键词： inherent safety process design simultaneous risk assessment risk footprint methanol process

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Numerical analysis on heat transfer enhancement by longitudinal vortex based on field synergy principle

WU Junmei, TAO Wenquan

《能源前沿（英文）》 2007年第1卷第3期页码 365-369 doi: 10.1007/s11708-007-0055-1

摘要： Three-dimensional numerical simulation results are presented for a fin-and-tube heat transfer surface with vortex generators. The effects of the Reynolds number (from 800 to 2 000) and the attack angle (30º and 45º) of a delta winglet vortex generator are examined. The numerical results are analyzed on the basis of the field synergy principle to explain the inherent mechanism of heat transfer enhancement by longitudinal vortex. The secondary flow generated by the vortex generators causes the reduction of the intersection angle between the velocity and fluid temperature gradients. In addition, the computational evaluations indicate that the heat transfer enhancement of delta winglet pairs for an aligned tube bank fin-and-tube surface is more significant than that for a staggered tube bank fin-and-tube surface. The heat transfer enhancement of the delta winglet pairs with an attack angle of 45º is larger than that with an angle of 30º. The delta winglet pair with an attack angle of 45º leads to an increase in pressure drop, while the delta winglet pair with the 30º angle results in a slight decrease. The heat transfer enhancement under identical pumping power condition for the attack angle of 30º is larger than that for the attack angle of 45º either for staggered or for aligned tube bank arrangement.

关键词： computational inherent mechanism staggered decrease transfer surface

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Numerical investigation and analysis of heat transfer enhancement in channel by longitudinal vortex based on field synergy principle

TAO Wenquan, WU Junmei

《能源前沿（英文）》 2008年第2卷第1期页码 71-78 doi: 10.1007/s11708-008-0001-x

摘要： 3-D numerical simulations were presented for laminar flow and heat transfer characteristics in a rectangular channel with vortex generators. The effects of Reynolds number (from 800 to 3 000), the attack angle of vortex generator (from 15° to 90°) and the shape of vortex generator were examined. The numerical results were analyzed based on the field synergy principle. It is found that the inherent mechanism of the heat transfer enhancement by longitudinal vortex can be explained by the field synergy principle, that is, the second flow generated by vortex generators results in the reduction of the intersection angle between the velocity and fluid temperature gradient. The longitudinal vortex improves the field synergy of the large downstream region of longitudinal vortex generator (LVG) and the region near (LVG); however, transverse vortex only improves the synergy of the region near vortex generator. Thus, longitudinal vortex can enhance the integral heat transfer of the flow field, while transverse vortex can only enhance the local heat transfer. The synergy angle decreases with the increase of Reynolds number for the channel with LVG to differ from the result obtained from the plain channel, and the triangle winglet performs better than the rectanglar one under the same surface area condition.

关键词： inherent mechanism integral surface rectanglar longitudinal

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Genome-wide association studies: inherent limitations and future challenges

null

《医学前沿（英文）》 2012年第6卷第4期页码 444-450 doi: 10.1007/s11684-012-0225-3

摘要：

Genome-wide association studies (GWAS) have achieved great success in identifying genetic variants related to complex human diseases such as cancer and have provided valuable insights into their genetic architecture. Recently, GWAS is quite the fashion in China. However, there are issues related to its nature. Enormous work needs to be done in the post-GWAS era. Deep sequencing followed by functional studies will be needed to elucidate the underpinning biological mechanisms and further translate GWAS findings into medical practice. Along with pharmacogenomics, the success of GWAS in identifying genetic risk factors and genetic differences in drug response has been gradually enabling personalized medicine. In this article, we used hepatocellular carcinoma (HCC) as an example to demonstrate some of the inherent limitations and summarized future challenges of GWAS.

关键词： genome-wide association studies (GWAS) genetic variant cancer limitation challenge

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基于本质安全的工业事故风险管理方法研究

吴宗之

《中国工程科学》 2007年第9卷第5期页码 46-49

摘要：

从风险管理角度对生产过程中的安全防护方法进行了分类和论述，提出了基于本质安全思想的工业事故综合风险管理方法与程序，其核心内容是在常规的危险辨识和风险评价基础上，优先应用本质安全原理来减少、消除危险，综合采用无源安全措施、有源安全措施或多层安全防护措施与功能安全标准，将风险降低至可接受水平；提出了本质安全应与清洁生产、绿色化学、循环经济同等纳入优先发展的技术和政策等建议。

关键词：本质安全风险管理事故预防安全设计

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Development and testing of a wireless smart toolholder with multi-sensor fusion

《机械工程前沿（英文）》 2023年第18卷第4期 doi: 10.1007/s11465-023-0774-y

摘要： The smart toolholder is the core component in the development of intelligent and precise manufacturing. It enables in situ monitoring of cutting data and machining accuracy evolution and has become a focal point in academic research and industrial applications. However, current table and rotational dynamometers for milling force, vibration, and temperature testing suffer from cumbersome installation and provide only a single acquisition signal, which limits their use in laboratory settings. In this study, we propose a wireless smart toolholder with multi-sensor fusion for simultaneous sensing of milling force, vibration, and temperature signals. We select force, vibration, and temperature sensors suitable for smart toolholder fusion to adapt to the cutting environment. Thereafter, structural design, circular runout, dynamic balancing, static stiffness, and dynamic inherent frequency tests are conducted to assess its dynamic and static performance. Finally, the smart toolholder is tested for accuracy and repeatability in terms of force, vibration, and temperature. Experimental results demonstrate that the smart toolholder accurately captures machining data with a relative deviation of less than 1.5% compared with existing force gauges and provides high repeatability of milling temperature and vibration signals. Therefore, it is a smart solution for machining condition monitoring.

关键词： wireless smart toolholder multi-sensor fusion circular runout dynamic balancing static stiffness dynamic inherent frequency

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Reduction of rough set attribute based on immune clone selection

LIANG Lin, XU Guang-hua

《机械工程前沿（英文）》 2006年第1卷第4期页码 413-417 doi: 10.1007/s11465-006-0049-4

摘要： A novel attribute reduction approach of rough set based on immune clone selection is proposed. In this method, the approximation quality and attribute set were adopted as evolution object and antibody, respectively. On the basis of the inherent distribution within the immune response, the global optimization of the antibody was realized through parallel local optimization. Moreover, the diversity of the antibody population was maintained with the affinity maturation and renewal of the antibody. Thus, the stable multi-optimal solutions can be preserved. In addition, the machinery fault data were analyzed by this method, and the attribute reduction sets were obtained further to satisfy the demand of feature selection in machinery diagnosis.

关键词： inherent distribution maturation evolution diversity antibody

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Theory and method of mechanism system design

Huijun ZOU, Qinghua LIANG, Qing ZHANG

《机械工程前沿（英文）》 2010年第5卷第4期页码 399-411 doi: 10.1007/s11465-010-0116-8

摘要： Conceptual design is the most critical and creative phase of design. Recently, increasing attention has been directed to supporting conceptual-level computer aided creative design and its theories and methodologies. Specifically, for conceptual design of mechanical products, this paper presents a novel function solving model for mechanical product design and highlights the importance of systematic synthesis to achieve creative design. Then it builds a framework as a function-effect-process-action- mechanisms (FEPAM) mapping process, which enables creative design on the basis of conceiving different action schemes. After that, several key points are elaborated including 1) representing and decomposition methods of functions and motion behaviors; 2) action scheme representing method based on network plan techniques; and 3) variation and creation methods based on action scheme transformations.

关键词： mechanism system creative design process model function solving model process action procedure mechanisms knowledge base principle of mechanism system composition

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Formation mechanism and modeling of surface waviness in incremental sheet forming

《机械工程前沿（英文）》 2022年第17卷第2期 doi: 10.1007/s11465-022-0679-1

摘要： Improving and controlling surface quality has always been a challenge for incremental sheet forming (ISF), whereas the generation mechanism of waviness surface is still unknown, which impedes the widely application of ISF in the industrial field. In this paper, the formation mechanism and the prediction of waviness are both investigated through experiments, numerical simulation, and theoretical analysis. Based on a verified finite element model, the waviness topography is predicted numerically for the first time, and its generation is attributed to the residual bending deformation through deformation history analysis. For more efficient engineering application, a theoretical model for waviness height is proposed based on the generation mechanism, using a modified strain function considering deformation modes. This work is favorable for the perfection of formation mechanism and control of surface quality in ISF.

关键词： surface waviness incremental sheet forming numerical simulation formation mechanism deformation history

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Autogenous healing mechanism of cement-based materials

《结构与土木工程前沿（英文）》页码 948-963 doi: 10.1007/s11709-023-0960-3

摘要： Autogenous self-healing is the innate and fundamental repair capability of cement-based materials for healing cracks. Many researchers have investigated factors that influence autogenous healing. However, systematic research on the autogenous healing mechanism of cement-based materials is lacking. The healing process mainly involves a chemical process, including further hydration of unhydrated cement and carbonation of calcium oxide and calcium hydroxide. Hence, the autogenous healing process is influenced by the material constituents of the cement composite and the ambient environment. In this study, different factors influencing the healing process of cement-based materials were investigated. Scanning electron microscopy and optical microscopy were used to examine the autogenous healing mechanism, and the maximum healing capacity was assessed. Furthermore, detailed theoretical analysis and quantitative detection of autogenous healing were conducted. This study provides a valuable reference for developing an improved healing technique for cement-based composites.

关键词： autogenous healing cement-based materials healing mechanism aggregation effect

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Optimal design of a linkage–cam mechanism-based redundantly actuated parallel manipulator

《机械工程前沿（英文）》 2021年第16卷第3期页码 451-467 doi: 10.1007/s11465-021-0634-6

摘要： A redundantly actuated parallel manipulator (RAPM) with mixed translational and rotational degrees of freedom (DOFs) is challenged for its dimensionally homogeneous Jacobian modeling and optimal design of architecture. In this paper, a means to achieve redundant actuation by adding kinematic constraints is introduced, which reduces the DOFs of the end-effector (EE). A generic dimensionally homogeneous Jacobian is developed for this type of RAPMs, which maps the generalized velocities of three points on the EE to the joint velocities. A new optimization algorithm derived from this dimensionally homogeneous Jacobian is proposed for the optimal design of this type of RAPMs. As an example, this paper presents a spatial RAPM involving linkages and cam mechanisms. This RAPM has 4 DOFs and 6 translational actuations. The linkage lengths and the position of the universal joints of the RAPM are optimized based on the dimensionally homogeneous Jacobian.

关键词： redundant actuation parallel manipulator linkage–cam mechanism Jacobian optimal design

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Cryogenic minimum quantity lubrication machining: from mechanism to application

《机械工程前沿（英文）》 2021年第16卷第4期页码 649-697 doi: 10.1007/s11465-021-0654-2

摘要： Cutting fluid plays a cooling–lubrication role in the cutting of metal materials. However, the substantial usage of cutting fluid in traditional flood machining seriously pollutes the environment and threatens the health of workers. Environmental machining technologies, such as dry cutting, minimum quantity lubrication (MQL), and cryogenic cooling technology, have been used as substitute for flood machining. However, the insufficient cooling capacity of MQL with normal-temperature compressed gas and the lack of lubricating performance of cryogenic cooling technology limit their industrial application. The technical bottleneck of mechanical–thermal damage of difficult-to-cut materials in aerospace and other fields can be solved by combining cryogenic medium and MQL. The latest progress of cryogenic minimum quantity lubrication (CMQL) technology is reviewed in this paper, and the key scientific issues in the research achievements of CMQL are clarified. First, the application forms and process characteristics of CMQL devices in turning, milling, and grinding are systematically summarized from traditional settings to innovative design. Second, the cooling–lubrication mechanism of CMQL and its influence mechanism on material hardness, cutting force, tool wear, and workpiece surface quality in cutting are extensively revealed. The effects of CMQL are systematically analyzed based on its mechanism and application form. Results show that the application effect of CMQL is better than that of cryogenic technology or MQL alone. Finally, the prospect, which provides basis and support for engineering application and development of CMQL technology, is introduced considering the limitations of CMQL.

关键词： cryogenic minimum quantity lubrication (CMQL) cryogenic medium processing mode device application mechanism application effect

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Review on mechanism and process of surface polishing using lasers

Arun KRISHNAN, Fengzhou FANG

《机械工程前沿（英文）》 2019年第14卷第3期页码 299-319 doi: 10.1007/s11465-019-0535-0

摘要： Laser polishing is a technology of smoothening the surface of various materials with highly intense laser beams. When these beams impact on the material surface to be polished, the surface starts to be melted due to the high temperature. The melted material is then relocated from the ‘peaks to valleys’ under the multidirectional action of surface tension. By varying the process parameters such as beam intensity, energy density, spot diameter, and feed rate, different rates of surface roughness can be achieved. High precision polishing of surfaces can be done using laser process. Currently, laser polishing has extended its applications from photonics to molds as well as bio-medical sectors. Conventional polishing techniques have many drawbacks such as less capability of polishing freeform surfaces, environmental pollution, long processing time, and health hazards for the operators. Laser polishing on the other hand eliminates all the mentioned drawbacks and comes as a promising technology that can be relied for smoothening of initial topography of the surfaces irrespective of the complexity of the surface. Majority of the researchers performed laser polishing on materials such as steel, titanium, and its alloys because of its low cost and reliability. This article gives a detailed overview of the laser polishing mechanism by explaining various process parameters briefly to get a better understanding about the entire polishing process. The advantages and applications are also explained clearly to have a good knowledge about the importance of laser polishing in the future.

关键词： laser polishing surface roughness process parameters mechanism

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Creation and integration mechanism of instrumentation flexible developing system

Xiaoli XU, Qiushuang LIU

《机械工程前沿（英文）》 2011年第6卷第2期页码 235-240 doi: 10.1007/s11465-011-0122-5

摘要：

To solve many key technical problems during the development of modern instrumentation system integration and provide a new mode and fundamental technical equipment for the research and development (R&D) of modern instrumentation products, based on the concept of an instrumentation flexible developing system (IFDS), this paper discusses the creation and open flexible integration mechanism, perfects the integrated supporting environment and integrated system of the flexible interconnection, and constructs the new flexible integrated system. Based on the operation mechanism of the modern instrumentation developing system and the research and optimization of the rapid integration design method, the paper emphasizes the dynamic integrating method of multiple types of knowledge in a modern instrument R&D system, to effectively utilize the rich integrated resource and achieve rapid integration of the system. Applications show that the new IFDS can improve the integration level and efficiency of R&D of the modern instrumentation system, enforce the reliability of the system, shorten the R&D period, and reduce the development costs.

关键词： modern instrumentation developing flexible interconnection flexible integration mechanism rapid integration system dynamic integrating method